La Roche-Posay Derm AOX Intense Anti-Wrinkle Radiance Serum
1 fl. oz. for $59.95
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Although this water-based serum contains some intriguing anti-aging ingredients, such as antioxidants, it cannot slow the aging process as claimed. No skin-care product can truly stop the clock, but lots of them can help your skin function in a younger, healthier manner.

Overall this serum falls into the same trap many others do, which is spotlighting one or two ingredients as being the best when research doesn’t show that to be the case. This time the ingredients du jour are carnosine and pycnogenol, an antioxidant derived from a species of pine tree. Both have value for skin, but neither is the end all, be all when it comes to anti-aging. Carnosine is composed of amino acids and, when it comes to wrinkles, it is believed to help reduce glycation in skin. Glycation involves the bonding of a sugar molecule with a protein (such as collagen) or fat. When glycation occurs in our skin, the by-products it generates can weaken or destroy collagen, leading to more wrinkles. There is in vitro research showing that carnosine, when introduced to cells that generate collagen, can help mitigate the damaging effects of glycation (Sources: Journal de la Societe de Biologie, volume 201, 2007, pages 185–188; and Pathologie-biologie, September 2006, pages 396–404) due to its antioxidant action, but that would be true of any potent antioxidant that shows up in skin-care products. Given that half of the beneficial ingredients in this serum are listed after the preservative, this doesn’t end up being one of the better serums available.

Last Updated:04.06.2015
Jar Packaging:No
Tested on animals:Yes
Community Reviews

Age prevention and correction. Slows the skin aging process. Smoothes wrinkles and restores radiance. Formulated Carnosine, a molecule stemming from diabetes research, to inhibit the glycation process and help maintain skin suppleness. Also formulated with Pycnogenol, one of the world's most powerful antioxidants², to neutralize free radicals + Vitamin E and Vitamin C, to help restore skin structure, smooth skin texture and increase radiance.


Water, Glycerin, PEG-20, Mis-PEG-18 Methyl Ether Dimethyl Silane, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Limanthes Alba Seed Oil/Meadowfoam Seed Oil, Carnosine, Ascorbic Acid, Octyldodecanol, Tocopherol, Sodium Styrene/MA Copolymer, Sodium Hydroxide, Sodium Hyaluronate, Phenoxyethanol, Ammonium Polyacryldimethyl Taurate, Pinus Pinaster Extract, Pinus Pinaster Bark/Bud Extract, Xanthan Gum, Pentasodium Ethylenediamine Tetramethylene Phosphate, Caprylyl Glycol, Capryloyl Salicylic Acid, Carbomer, Disodium EDTA, Fragrance

Brand Overview

La Roche-Posay At-A-Glance

L'Oreal-owned La Roche-Posay has a pharmaceutical lineage based in France, and the company speaks of their thermal spring water as the cornerstone of their commitment to dermatological skin care. In fact, the name La Roche-Posay comes from the French town that is the source of this water, which is said to be a rich in selenium. While selenium is an element that has potent antioxidant ability, it's unclear how much the water La Roche-Posay uses contains, since all water has to go through purification processes to be to used in cosmetic products.

That aside, this brand does have a number of standout products, including some good sunscreens and anti-aging treatments. Another positive: All of its skincare is packaged in containers that will keep beneficial products protected from light and air (no jar packaging here!). Unfortunately there are some missteps, namely that some otherwise-excellent products include potentially-irritating amounts of alcohol, fragrance, or other irritants. The line could also benefit from additional products that contain more state-of-the-art ingredients. Still, for a no-frills approach to serious skin care, there are some finds to be had!

For more information about La Roche-Posay, owned by L'Oreal, call (888) 577-5226 or visit www.laroche-posay.com.

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