Jan Marini Skin Research, Inc. Clean Zyme
4 fl. oz. for $28
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Despite all the talk about how papaya (source of the enzyme papain, one of the “resurfacing agents in this exfoliant) works on skin, there is no research showing it to have exfoliating properties on skin, and definitely none showing it to be preferred over AHAs or BHA. The Web site www.naturaldatabase.com states that there is insufficient reliable information to support the effectiveness of papaya. Note: Persons allergic to latex, kiwi, or figs are very likely to have a negative reaction to papain, the enzyme component of papaya (Source: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology, August 2004, pages 1251–1258).

What’s particularly problematic about this product is the amount of alcohol it contains. Alcohol causes dryness, free-radical damage, and irritation that hurts your skin’s healing process and ability to produce healthy collagen. This product would be a mistake for anyone hoping to look younger!

Lastly, the fruit and sugar cane extracts cannot function the same as AHAs such as glycolic or lactic acids. There is no research proving these extracts are preferred to a well formulated AHA or BHA product.

Last Updated:03.15.2011
Jar Packaging:No
Tested on animals:No
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Clean Zyme and Skin Zyme are supplemental home care exfoliation products that have the ability to digest dead skin cells without harming sensitive or irritated tissues. Benefits of other resurfacing agents are dramatically accelerated and desired results are more rapidly obtained with regard to skin rejuvenation, acne, hyperpigmentation and scar reduction. Clean Zyme and Skin Zyme is the definitive home exfoliator as well as an excellent clinical treatment as an adjunct to facial services and other facial procedures.


Water, Alcohol, Butylene Glycol, Aloe Barbadensis Leaf Juice, Honey, Decyl Glucoside, Orange Flower Extract, Papaya Fruit Extract, Orange Fruit Extract, Lemon Fruit Extract, Sugar Maple Extract, Sugar Cane Extract, Vaccinium Myrtillus Fruit Extract, Orange Peel Oil, Tocopheryl

Brand Overview

Jan Marini Skin Research, Inc. At-A-Glance

Strengths: Most of the products are fragrance- and colorant-free; excellent AHA and retinol options, including an AHA combined with sunscreen; the water-soluble cleansers.

Weaknesses: Expensive; some categories contain ingredients (growth factors, hormones, and interferon) with unreliable track records or whose long-term risks, if any, remain unknown; sunscreens that lack sufficient UVA-protecting ingredients; jar packaging; Marini Lash isn't as exciting as Marini’s former lash-enhancing products.

Jan Marini Skin Research, Inc., was founded, of course, by Jan Marini, who originally started out marketing products for M.D. Formulations. Thus, it isn't surprising to find that her own line is also aimed at dermatologists, aestheticians, and plastic surgeons, much the way M.D. Formulations is. In direct contrast to many of the other skin-care lines in this niche market, Marini’s line stands out with its selection of far more realistic and varied skin-care products. First, there are no spiraling-out-of-control ingredient lists where everything is thrown in except the kitchen sink. Then, and more important, you will find some well-formulated products that include sunscreens, skin-lightening options, vitamin C products, and good glycolic acid–based alpha hydroxy acid (AHA) products, along with some outstanding retinol options.

It is interesting to observe that Marini attributes the research for her "topical form of lipid (fat) soluble Vitamin C that is stable and able to be absorbed" to the form "developed in conjunction with physician researcher Nicholas Perricone, M.D." Of course, Perricone has his own version of vitamin C products, which are quite similar to Marini's in that they also contain ascorbyl palmitate. That being the case, given that he claims his are the best ever with the highest concentration of the stuff, we wonder if she would now agree with his findings? At least compared to her former partners at M.D. Formulations, Marini's information about vitamin C is more accurately based (it's backed by published research) and there's only a minimal amount of hyperbole. In fact, when it comes to the information Marini and team present to the professionals who retail their products, this line wins high marks for its close-to-accurate information about how skin ages, what can be done to minimize and prevent future signs of aging, and the effects various products have on skin. Of course, you're supposed to believe her products have all the answers, but that's what the reviews below will elucidate.

For more information about Jan Marini Skin Research, Inc., call (888) 695-2611 or visit www.janmarini.com.

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