Peter Thomas Roth

Neuroliquid Volufill Youth Serum

1.70 fl. oz. for $ 120.00
Expert Rating

Expert Reviews

Community Reviews



Brand Overview

To start, there is nothing neurological or “volume filling” about this product though we love the name from a marketing point of view. This serum from Peter Thomas Roth comes with the claim that its special “Volufill” complex can help smooth out the appearance of wrinkles because it stimulates collagen production. While it can indeed help skin build collagen (something any well formulated skincare product can do) it doesn’t work as miraculously as claimed and isn’t worth of the price tag. However, aside from claims and pricing this is still a very well done serum!

This formula is lightweight (it has a watery texture) and absorbs without feeling greasy. The “Volufill” complex the brand talks about is actually a combination of amino acids (19 of them), some of which are right up front at the beginning of the ingredient list. While amino acids won’t stimulate collagen production in of themselves, they are good water-binding agents, and some have antioxidant properties as well. All this is positive news, as this helps to repair skin’s moisture barrier, which will definitely contribute to making skin appear more rejuvenated and as a result build more collagen. There are also some peptides, which can serve as cell-communicating ingredients, but peptides having benefit are more theory than fact, along with a few antioxidants, too. Best of all, the container will keep them stable, and the formula is fragrance-free (we love seeing this and so will your skin)!

We want to address Peter Thomas Roth’s claims that this serum can restore fullness and reduce a hollowed-out look. We wish this weren’t the case, but despite the name, a serum, even one with more hyaluronic acid than this one contains, which isn’t much, simply cannot do this. This product in no way shape or form will restore lost facial volume.

The face loses volume, plumpness, and shape when one or more of its 20 fat pads slip out of place or become depleted with age, while sun damage causes other supportive elements to breakdown as well. This, combined with the effects of gravity plus bone loss that occurs with age explains why an aging face can begin to look hollow and begin to sag—yet the chief drivers of this happening cannot be corrected by skin care. It’s simply an area of facial aging where skin care has limitations that cosmetic corrective procedures (like dermal fillers) can step in and correct.

So although this isn’t miracle product that will get rid of your wrinkles and restore a plump, full look to your face, it is a very good moisturizing serum that can improve skin’s appearance over time, and can definitely be added as part of a good anti-aging skincare routine for those with normal to dry skin.


Contains a good amount of water-binding amino acids.

  • Contains peptides which can serve as cell-communicating ingredients.
  • Has antioxidants that can serve to repair free-radical damage.
  • Packaged in a container that will keep its light- and air-sensitive ingredients stable.
  • Fragrance-free.


  • Pricey, given that it can’t “fill” wrinkles or reduce a hollow look as claimed.

Jar Packaging: No
Tested on animals: Yes

Patent pending Neuroliquid helps restore the appearance of fullness, skin appears rejuvenated and radiant, improves the appearance of deep wrinkles.

Proline, Threonine, Serine, Arginine, Water/Aqua/Eau, Isoleucine, Glycine, Glycerin, Lysine, Histidine, Leucine, Acetyl Hydroxyproline, Glutamic Acid, Aspartic Acid, Alanine, Tyrosine, Methionine, Phenylalanine, Isopropyl Myristate, Palmitoyl Tripeptide- 5, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Acetyl Tetrapeptide-9, Hexapeptide-2, Soluble Collagen, Cysteine, Valine, Glutamine, Sodium Hyaluronate, Sodium PCA, Butylene Glycol, Diphenylsiloxy Phenyl Trimethicone, Ethylhexylglycerin, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Polymethylsilsesquioxane, Soy Amino Acids, Algae Extract, Yeast Extract, Acacia Seyal Gum Extract, Propylene Glycol, Pentylene Glycol, Trideceth-9, PEG-40 Hydrogenated Castor Oil, Sodium Borate, Mica, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate.

Peter Thomas Roth At-A-Glance

Peter Thomas Roth is a large but straightforward line with mostly uncomplicated formulations that, for the most part, are quite good and state-of-the-art. Unlike many product lines, most of the acne, AHA, BHA, sunscreen, and moisturizing products contain what they should to be effective and helpful for skin.

Even more impressive are the well-formulated cleansers, sunscreens, AHA products, and skin brighteners. The moisturizers have improved somewhat, and most are now packaged so that the light- and air-sensitive ingredients remain stable. In fact, Roth's packaging deserves special mention because it is exceptionally utilitarian.

After all that glowing praise, what you should be aware of are the instances of products containing potential irritants (noted in their respective reviews) as well as the products in jar packaging that contain ingredients which are sensitive to air and light.

For more information about Peter Thomas Roth, call (800) PTR-SKIN or visit www.peterthomasroth.com.

About the Experts

The Beautypedia team consists of skin care and makeup experts personally trained by the original Cosmetics Cop and best-selling beauty author, Paula Begoun. We’re fascinated by skin care and makeup products and thrilled when they meet or exceed our expectations, but we’re also disappointed when they fail to perform as claimed, are wildly overpriced, or contain ingredients scientific research has proven can hurt skin.

Our mission has always been to help you find the best products for your skin, no matter your budget or preferences. Beautypedia’s thorough and insightful reviews cut through the hype and provide reliable recommendations for all ages, skin types, and skin tones.

This post may contain affiliate links. Please read our terms of use here.